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Main Street Kirksville

Main Street Kirksville

Where People Make the Difference

Main Street Kirksville is the historic downtown area of Kirksville, Missouri, located just a short walk from Truman State University and A.T. Still University. It serves as a vibrant community hub with a variety of restaurants, shops, the Kirksville Arts Association, a local Farmers Market, an 8-screen cinema, and seasonal festivals. The area is dedicated to fostering economic development, revitalizing and preserving downtown, and promoting it as an exciting place to shop, dine, live, work, entertain, invest, and own a business. The organization behind these efforts, formerly known as the Kirksville Downtown Improvement Committee, rebranded as Main Street Kirksville and follows a structured renovation approach through the Missouri Main Street Program focusing on promotion, design, economic vitality, and organization. Main Street Kirksville also hosts community events such as holiday markets and parades, making it the lively heart of Kirksville’s social and commercial life.

Kirksville, MO Downtown

History


Founded in 2002

Main Street Kirksville is organized under the Missouri Nonprofit Corporation Law and received its articles of incorporation from the State of Missouri, Secretary of State’s office on December 3, 2002.  The corporation is a not-for-profit corporation, organized and existing under the provisions of Chapter 355 of the statutes, within the meaning of Section 501 (c) (3) of the Internal Revenue Code.   

The purpose of Main Street Kirksville is to strengthen the center of the Kirksville community by creating a positive image, fostering economic development, and revitalizing and preserving downtown Kirksville, while promoting the area as an exciting place to shop, dine, live, work, be entertained, invest, and own a business. 

View AllUpcoming Events


Main Street Kirksville Partner Gallery 104
First Friday at Gallery 104: Art on the Square, 104 N Franklin St, Kirksville, MO 63501
Jul 03, 2026, 5:00 PM CDT
Kirksville, MO
Kick off your weekend with a free early-evening outing on the square with refreshments and conversation.
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Main Street Kirksville Partner Gallery 104
First Friday at Gallery 104: Art on the Square, 104 N Franklin St, Kirksville, MO 63501
Aug 07, 2026, 5:00 PM CDT
Kirksville, MO
Kick off your weekend with a free early-evening outing on the square with refreshments and conversation.
Read More
Main Street Kirksville Partner Gallery 104
First Friday at Gallery 104: Art on the Square, 104 N Franklin St, Kirksville, MO 63501
Sep 04, 2026, 5:00 PM CDT
Kirksville, MO
Kick off your weekend with a free early-evening outing on the square with refreshments and conversation.
Read More
Main Street Kirksville Whiskey & Turkey Festival
Whiskey & Turkey Festival
Sep 12, 2026, 5:00 PM CDT
Kirksville, MO
Saturday, September 12, 2026 - 5 PM - 11 PM - Downtown
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Main Street Kirksville Partner Gallery 104
First Friday at Gallery 104: Art on the Square, 104 N Franklin St, Kirksville, MO 63501
Oct 02, 2026, 5:00 PM CDT
Kirksville, MO
Kick off your weekend with a free early-evening outing on the square with refreshments and conversation.
Read More

View AllRecent Posts


Main Street Kirksville Receives $5,000 Missouri Humaniti... Main Street Kirksville and Missouri Humanities Announce 2026 Whiskey & Turkey Festival Grant
Downtown Live was a hit!What an incredible Downtown Live! As part of the Special Olympics Missouri State Summer Games weekend, we were thrilled to welcome famil...
Celebrating National Small Business Week in Downtown Kir... National Small Business Week is here, and there’s no better place to celebrate than Historic Downtown Kirksville. From May 3–9, communit...